Description
Information about the drug
Cialis is used for medical purposes to overcome sexual disorders in men, namely erectile dysfunction. The active component of this drug is Tadalafil. This means works as follows, getting into the blood active components provoke oval blood vessel cells to the intensified production of Nitric Oxide. This leads to a relaxation of smooth muscles in the arteries. As a result, the capacity of the blood vessels is significantly increased, as a result, tissues are saturated with a large amount of oxygen and nutrients.
For bodybuilding, this drug is a very important component, as it allows the development of the circulatory system, which in turn allows the muscles to develop faster, in addition to this, the athlete receiving Cialis increases endurance and strength. These two factors play a key role in grueling training.
Taking Tadalafil Citrate before training, the athlete feels the increased pumping (pumping) of the working group of muscles, this is connected with the fact that more blood flows into the muscles, and the received sensation remains up to 24 hours. During this period there is an active construction of the circulatory system, new blood vessels appear, which facilitates the growth of muscle tissue.
Pharmacology
Suction. After oral administration, tadalafil is rapidly absorbed. The average plasma Cmax is reached on average 2 hours after ingestion. The rate and extent of absorption of tadalafil are independent of food intake, so the drug can be taken without regard to food. The time of administration (morning or evening) does not significantly affect the rate and extent of absorption.
Distribution. The average distribution volume is about 63 liters. At therapeutic concentrations, 94% of tadalafil binds to plasma proteins. In healthy individuals, <0.0005% of the administered dose is detected in semen.
Metabolism. Tadalafil is mainly metabolized with the participation of the isoenzyme CYP 3A4 cytochrome P450. The main circulating metabolite is methylcatecholglucuronide. This metabolite is 13,000 times less active against PDE-5 than tadalafil. Therefore, it can be assumed that this metabolite is not clinically significant at detectable concentrations.
Breeding. In healthy individuals, the average T½ is 17.5 hours. Tadalafil is excreted mainly in the form of inactive metabolites, mainly with feces (about 61% of the dose) and to a lesser extent with urine (about 36% of the dose).
Applying
In general, the use of this drug, resorts to more experienced athletes and professionals. It should also be recalled that sexual arousal when using Cialis occurs only in the case of stimulation, so spontaneous erection should not be expected.
The active substance of this drug works for 36 hours. This means that throughout this time, your circulatory system will develop at an accelerated rate.
The dosage of the drug depends on whether the athlete is familiar with its effect or is just beginning to get acquainted with Tadalafil Citrate. To begin with, take 10 mg of a drug (half-pill), this will allow you to evaluate Cialis Teragon Labs effects. Experienced athletes take 20 mg approximately 45 minutes before sports, this time is enough to make the drug work. Cialis Teragon Labs uses can be quite a long time, because it is not addictive
Cialis Teragon Labs Side effects
This product is very powerful, so if you are taking any other medications, you should consult a doctor about the combination. This product is practically harmless, but with the wrong application, the following complications may occur:
- Diarrhea;
- Dizziness;
- Stomach ache;
- Joint pain;
- Bleeding from the nose.
Contraindications:
- hypersensitivity to tadalafil or to any substance that is part of the drug
- taking preparations containing any organic nitrates
- diseases of the cardiovascular system: myocardial infarction over the past 90 days, unstable angina, the occurrence of an attack of angina pectoris during intercourse, heart failure II-IV classes according to the classification of the New York Cardiology Association (NYHA), which has developed over the past 6 months, uncontrolled arrhythmia, arterial hypotension (blood pressure less than 90/50 mm Hg), uncontrolled hypertension, ischemic stroke over the past 6 months
- vision loss due to non-arteritis-related anterior ischemic optic neuropathy (NAPION) (regardless of association with PDE5 inhibitors)
- frequent (more than 2 times a week) use in patients with chronic renal failure (CC less than 30 ml / min)
- hereditary galactose intolerance, Lapp-lactase deficiency and glucose-galactose malabsorption
- children and adolescents under 18 years
Special Notes:
- Before starting any uses, the doctor must evaluate the patient’s cardiovascular system, since there is a certain degree of risk.
- Cases of visual impairment have been reported during the use of Cialis and other PDE-5 inhibitors. The doctor should warn the patient about the need to stop using tadalafil and seek medical help in case of sudden loss of vision.
- Cialis should be used with caution in patients with a predisposition to priapism (for example, with sickle cell anemia, multiple myeloma, or leukemia).
- The safety data for a single dose of Cialis in patients with severe hepatic insufficiency is limited. When prescribing Cialis to such patients, a thorough clinical evaluation is required.
- It is necessary to prescribe Cialis with caution to patients taking α1-adrenergic receptor blockers, since in some cases, concomitant use of these drugs can lead to symptomatic hypotension.
- The safety and effectiveness of the combination of Cialis and other PDE-5 inhibitors or other drugs have not been studied, so you can not take Cialis in such combinations. Like other PDE-5 inhibitors, tadalafil is able to exert a systemic vasodilator effect, which can lead to a transient decrease in blood pressure. Therefore, before starting treatment, the doctor should assess the degree of propensity of the patient to adverse vasodilator effects.
- The drug should not be prescribed to patients with rare hereditary forms of galactose intolerance, glucose-galactase malabsorption syndrome and Lapp lactase deficiency due to the content of lactose monohydrate.
Warning!
This drug is medical product and requires following recommendations of using and storing. It should be stored in the cool dark place, avoiding direct sunlight. It’s also necessary to prevent applying this drug by children.
You MUST consult with your attending physician before you start using this drug. We also ask you to take into account that this drug may cause some side effects, some of them can be life-threatening. If you notice any disturbing symptoms you should to contact with your physician. In some cases, it is necessary to stop taking the drug for a while. Also you must inform your doctor if you taking this drugs with other medicines. So physician can prescribe proper treatment and help to avoid any unpleasant adverse effects.
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